Article

Dr Love's zebrafish

Dr Don Love and his team at Auckland University are using zebrafish to investigate heritable diseases like Duchenne muscular dystrophy.

He met with Year 13 Biology students to discuss his work and some of the techniques commonly used in his laboratory.

Watch clips of Dr Love explaining:

  • What makes zebrafish good models for some human diseases – and not others

  • Genes, chromosomes and genomes – and what you need to know in order to create a targeted gene effect

  • The importance of PCR and DNA sequencing in identifying fish with a specific mutation

  • Why the future represents a ‘new dawn’ in biological research

  • Careers prospects for geneticists in New Zealand

To find out more about Don’s work, see the article: Zebrafish make a difference.

Students participating in this 2007 video conference were from:

  • Stratford High School

  • Wellington College

  • Waipa Area School

Video clips

Why are zebrafish good research models?

Animal models are often needed to understand the complexity of disease and to find treatments. What makes vertebrates like zebrafish good research models?

Rights: The University of Waikato

But it's a fish!

Blood, nerves, eyes – Auckland University's Dr Love explains why it all depends on what you're looking for.

Rights: The University of Waikato

Are zebrafish good models?

According to Dr Love, what makes zebrafish useful in the study of a disease like muscular dystrophy?

Rights: The University of Waikato

Insults equal change

What are six ways to insult a zebrafish? Students from Stratford High School ask Auckland University's Dr Love.

Rights: The University of Waikato

Designing genetic change

Dr Love's work at Auckland University involves altering the gene expression of zebrafish. Here, he explains to Year 13 students from Taipa and Stratford what he needs to know first.

Rights: The University of Waikato

Checking for mutations

How can PCR and DNA sequencing be used to identify whether a specific mutation is present or not?

Rights: The University of Waikato

It's not just genes

What does Dr Love think is the 'new dawn' for biological research?

Rights: The University of Waikato

The road is long (with many a winding turn...)

In 2001 the Sanger Institute and the Human Genome Project announced that they had both sequenced the human genome. We are on a long road to understanding the full implications of this information.

Rights: The University of Waikato

Research funding

There are several potential sources of funding for medical research programmes in New Zealand, but it's highly competitive. So where does Dr Love, investigating muscular dystrophy, get his funding from?

Rights: The University of Waikato

Career prospects in genetics

Auckland University's Dr Love suggests that recognition of science as a good investment will mean improved career opportunities for geneticists in New Zealand. Get his advice on your education and career options.

Rights: The University of Waikato

 

Published: 27 November 2007